Journal article

Baseline characteristics of patients with atypical haemolytic uraemic syndrome (aHUS): The Australian cohort in a global aHUS registry

Jacqueline Soraru, Nicole Isbel, Germaine Wong, Patrick Toby Coates, Murty Mantha, Abu Abraham, Rajiv Juneja, Danny Hsu, Fiona Brown, Bhadran Bose, David Mudge, Robert Carroll, Joshua Kausman, Peter Hughes, Thomas Barbour, Anne Durkan, Peter Mount, Darren Lee, Nicholas Larkins, Dwarakanathan Ranganathan Show all

Nephrology | WILEY | Published : 2020

Abstract

AIMS: To describe the baseline characteristics and treatment of Australian patients diagnosed with atypical haemolytic uraemic syndrome (aHUS) reported to the Global aHUS Registry. METHODS: Descriptive analysis of the Australian cohort with aHUS (n = 106) was undertaken for demographics, disease characteristics and prior treatment with eculizumab; comparing with the global cohort (n = 1688) for certain pre-specified disease characteristics. RESULTS: In Australia, almost two-thirds of patients diagnosed with aHUS were female and over 80% of patients were Caucasians, with similar proportions reported in the global cohort. Less than 6% of patients in the Australia and global cohorts were report..

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Grants

Funding Acknowledgements

Health Department of Western Australia, Grant/Award Number: Raine Foundation Clinical Research Fellowship; National Health and Medical Research Council, Grant/Award Number: Career Development Fellowship; Royal Australian College of Physicians, Grant/Award Number: Jacquot Research Foundation; University of Western Australia, Grant/Award Number: Raine Foundation Clinical Research Fellowship; Alexion Pharmaceuticals; Alexion Pharmaceuticals, Grant/Award Number: Honoraria for Advisory Board Membership and Educat