Journal article

Guidelines and definitions for research on epithelial-mesenchymal transition

Jing Yang, Parker Antin, Geert Berx, Cedric Blanpain, Thomas Brabletz, Marianne Bronner, Kyra Campbell, Amparo Cano, Jordi Casanova, Gerhard Christofori, Shoukat Dedhar, Rik Derynck, Heide L Ford, Jonas Fuxe, Antonio Garcia de Herreros, Gregory J Goodall, Anna-Katerina Hadjantonakis, Ruby JY Huang, Chaya Kalcheim, Raghu Kalluri Show all

Nature Reviews Molecular Cell Biology | NATURE PUBLISHING GROUP | Published : 2020

Abstract

Epithelial-mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migration and invasion. EMT occurs in a diverse range of physiological and pathological conditions and is driven by a conserved set of inducing signals, transcriptional regulators and downstream effectors. With over 5,700 publications indexed by Web of Science in 2019 alone, research on EMT is expanding rapidly. This growing interest warrants the need for a consensus among researchers when referring to and undertaking research on EMT. This Consensus Statement, mediated by 'the EMT International Association' (TEMTIA),..

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