Journal article

Clinical Application of Findings From Longitudinal Studies of Younger-Onset Dementia: Rapid Review and Recommendations

Samantha M Loi, Anita MY Goh, Mark Walterfang, Dennis Velakoulis

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | AMER PSYCHIATRIC PUBLISHING, INC | Published : 2020

Abstract

Younger-onset dementia (YOD) presents with heterogeneous symptoms, has a variety of etiologies, and can be difficult to diagnose. The authors conducted a rapid review of longitudinal YOD cohorts and their related substudies to evaluate current literature that may inform the clinical information provided to patients about the progression and duration of illness and to highlight areas for future research. Searches were conducted using MEDLINE, CINAHL, PubMed, PsycINFO, and Web of Science for articles published between January 1966 and June 2018. Four longitudinal YOD cohort studies and their related substudies were identified. Alzheimer's disease (AD) was reported as the most frequently occurr..

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