Expanding the Role for Immunotherapy in Triple-Negative Breast Cancer
Peter Savas, Sherene Loi
Cancer Cell | CELL PRESS | Published : 2020
PD-1 axis blockade, in combination with chemotherapy, improves outcomes in advanced triple-negative breast cancer that is PD-L1 positive. The phase 3 KEYNOTE-522 trial now shows that the addition of pembrolizumab to chemotherapy improves pathological complete response rates regardless of PD-L1 status and appears to improve survival.