Journal article

Association between Patient-Reported Outcomes and Time to Late Age-Related Macular Degeneration in the Laser Intervention in Early Stages of Age-Related Macular Degeneration Study.

Myra B McGuinness, Robert P Finger, Zhichao Wu, Chi D Luu, Fred K Chen, Jenifer J Arnold, Usha Chakravarthy, Robyn H Guymer, undefined Laser Intervention in Early Stages of Age-Related Macular Degeneration Study Group

Ophthalmology Retina | Elsevier | Published : 2020

Abstract

PURPOSE: To investigate the relationship between patient-reported outcome (PRO) questionnaire responses and time to late age-related macular degeneration (AMD; neovascular AMD [nAMD] or multimodal imaging [MMI]-defined atrophy) among individuals with bilateral large drusen, and the prognostic value of baseline PROs for 36-month AMD status. DESIGN: Exploratory analyses from a multicenter randomized controlled trial of an AMD intervention (Australian New Zealand Clinical Trials Registry identifier, ACTRN12612000704897). PARTICIPANTS: Sham treatment group of the Laser Intervention in Early Stages of Age-Related Macular Degeneration (LEAD) Study (n = 141; age, 50-88 years; 77% female). METHODS: ..

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