Journal article
Impact of Community Treatment with Ivermectin for the Control of Scabies on the Prevalence of Antibodies to Strongyloides stercoralis in Children
M Marks, S Gwyn, H Toloka, C Kositz, J Asugeni, R Asugeni, J Diau, JM Kaldor, L Romani, M Redman-Maclaren, D MacLaren, AW Solomon, DCW Mabey, AC Steer, D Martin
Clinical Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2020
DOI: 10.1093/cid/ciaa584
Open access
Abstract
The prevalence of antibodies to Strongyloides stercoralis was measured in 0-12-year-olds using a bead-based immunoassay before and after ivermectin mass drug administration (MDA) for scabies in the Solomon Islands. Seroprevalence was 9.3% before and 5.1% after MDA (P†=†.019), demonstrating collateral benefits of ivermectin MDA in this setting.
Grants
Awarded by Wellcome Trust
Funding Acknowledgements
The study was supported by a Wellcome Trust, Clinical PhD Fellowship (grant number 102807 to M. M.). The US Centers for Disease Control and Prevention paid the laboratory costs.