Journal article

Bleeding Severity in Percutaneous Coronary Intervention (PCI) and Its Impact on Short-Term Clinical Outcomes

Shashank Murali, Sara Vogrin, Samer Noaman, Diem T Dinh, Angela L Brennan, Jeffrey Lefkovits, Christopher M Reid, Nicholas Cox, William Chan

Journal of Clinical Medicine | MDPI | Published : 2020

Abstract

Bleeding severity in patients undergoing percutaneous coronary intervention (PCI), defined by the Bleeding Academic Research Consortium (BARC), portends adverse prognosis. We analysed data from 37,866 Australian patients undergoing PCI enrolled in the Victorian Cardiac Outcomes Registry (VCOR), and investigated the association between increasing BARC severity and in-hospital and 30-day major adverse cardiac and cerebrovascular events (MACCE) (a composite of mortality, myocardial infarction, stent thrombosis, target vessel revascularisation, or stroke). Independent predictors associated with major bleeding (BARC groups 3&5), and MACCE were also assessed. There was a stepwise increase in in-ho..

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Grants

Awarded by NHMRC Principal Research Fellowship


Funding Acknowledgements

Samer Noaman is supported by a scholarship from the NHMRC CRE-COI and National Heart Foundation Fellowship. Christopher Reid is supported by a NHMRC Principal Research Fellowship (1136372) and William Chan is supported by the Alfred Hospital Research Trust and the Harold Cora Brennan Benevolent Trust.