Comparison of clinical risk factors for incident fracture in obese and non-obese community-dwelling older men
David Scott, Markus J Seibel, Robert Cumming, Vasi Naganathan, Fiona Blyth, David G Le Couteur, David J Handelsman, Benjumin Hsu, Louise M Waite, Vasant Hirani
Bone | ELSEVIER SCIENCE INC | Published : 2020
BACKGROUND: Obese older adults have higher bone mineral density (BMD), but other characteristics of obesity may predispose these individuals to fracture. We aimed to compare clinical risk factors for incident fracture in obese and non-obese older men. METHODS: Body mass index (BMI) and body fat percentage were assessed at baseline by anthropometry and dual-energy X-ray absorptiometry, respectively, in 1625 community-dwelling men aged ≥70 years. Categories for non-obese and obese were <30 kg/m2and ≥30 kg/m2 for BMI, and 0.05) or body fat percentage (10.2 vs 10.6%, respectively; P > 0.05). Significant interactions were observed demonstrating that dementia increased hazard for incident any and..View full abstract
Awarded by National Health and Medical Research Council (NHMRC)
Awarded by NHMRC
This work was supported by the National Health and Medical Research Council (NHMRC; project grant number 301916) and the Ageing and Alzheimer's Institute. D.S. is supported by a NHMRC Career Development Fellowship (GNT1123014) and an NHMRC Investigator Grant (GNT1174886). The funding body had no role in study design; collection, analysis and interpretation of data; in the writing of the report; or in the decision to submit the article for publication.