Critical Review of Transcutaneous Vagus Nerve Stimulation: Challenges for Translation to Clinical Practice
JYY Yap, C Keatch, E Lambert, W Woods, PR Stoddart, T Kameneva
Frontiers in Neuroscience | Frontiers Media | Published : 2020
Several studies have illustrated that transcutaneous vagus nerve stimulation (tVNS) can elicit therapeutic effects that are similar to those produced by its invasive counterpart, vagus nerve stimulation (VNS). VNS is an FDA-approved therapy for the treatment of both depression and epilepsy, but it is limited to the management of more severe, intervention-resistant cases as a second or third-line treatment option due to perioperative risks involved with device implantation. In contrast, tVNS is a non-invasive technique that involves the application of electrical currents through surface electrodes at select locations, most commonly targeting the auricular branch of the vagus nerve (ABVN) and ..View full abstract
Awarded by Australian Research Council
PS and JY acknowledge funding support from the Australian Research Council (IC140100023) and Grey Innovation Pty Ltd.