Epidemic and Inter-epidemic Burden of Pediatric Human Parechovirus Infection in New South Wales, Australia, 2017-2018
Ameneh Khatami, Rebecca Burrell, Brendan J McMullan, William Rawlinson, Rodney C Givney, Jen Kok, Soren Alexandersen, Cheryl A Jones, Kristine K Macartney, Philip N Britton
The Pediatric Infectious Disease Journal | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020
BACKGROUND: Human parechovirus (HPeV) typically infects young children, and although infection is often asymptomatic, some types (eg, HPeV3) are associated with severe clinical manifestations, including central nervous system infection or sepsis-like syndrome, particularly affecting young infants. The third documented national epidemic of HPeV occurred in Australia in 2017-2018. METHODS: Four public laboratories that perform almost all of the HPeV PCR testing in New South Wales provided data regarding HPeV tests performed from July 1, 2017 to June 30, 2018. Limited demographic and clinical data were obtained from electronic medical records for laboratory test-positive cases that presented to..View full abstract
Awarded by National Health and Medical Research Council (NHMRC) equipment grant
Awarded by CREID NHMRC Centre for Research Excellence
Awarded by NHMRC early career fellowship
J.K. declares that this work was supported by the Prevention Research Support Program, funded by the New South Wales Department of Health. B.J.M. currently has funding from a University of Melbourne PhD scholarship. S.A. has funding from Deakin University, Barwon Health and the National Health and Medical Research Council (NHMRC) equipment grant (GNT9000413). C.A.J. has funding support from CREID NHMRC Centre for Research Excellence (GNT1102962). P.N.B. is funded by an NHMRC early career fellowship (GNT1145817) and this project received funding from the APPRISE NHMRC Centre for Research Excellence. The authors have no conflicts of interests to disclose.