Journal article
Study protocol and statistical analysis plan for the Liberal Glucose Control in Critically Ill Patients with Pre-existing Type 2 Diabetes (LUCID) trial
AP Poole, ME Finnis, J Anstey, R Bellomo, S Bihari, V Biradar, S Doherty, G Eastwood, S Finfer, CJ French, A Ghosh, S Heller, M Horowitz, P Kar, PS Kruger, MJ Maiden, J Mårtensson, CJ McArthur, SP McGuinness, PJ Secombe Show all
Critical Care and Resuscitation | AUSTRALASIAN MED PUBL CO LTD | Published : 2020
DOI: 10.51893/2020.2.oa3
Abstract
Background: Contemporary glucose management of intensive care unit (ICU) patients with type 2 diabetes is based on trial data derived predominantly from patients without type 2 diabetes. This is despite the recognition that patients with type 2 diabetes may be relatively more tolerant of hyperglycaemia and more susceptible to hypoglycaemia. It is uncertain whether glucose targets should be more liberal in patients with type 2 diabetes. Objective: To detail the protocol, analysis and reporting plans for a randomised clinical trial — the Liberal Glucose Control in Critically Ill Patients with Pre-existing Type 2 Diabetes (LUCID) trial — which will evaluate the risks and benefits of targeting a..
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