Measuring atrial stasis during sinus rhythm in patients with paroxysmal atrial fibrillation using 4 Dimensional flow imaging. 4D flow imaging of atrial stasis
Benedict T Costello, Aleksandr Voskoboinik, Abdul M Qadri, Murray Rudman, Mark C Thompson, Ferris Touma, Andre La Gerche, James L Hare, Stavroula Papapostolou, Jonathan M Kalman, Peter M Kistler, Andrew J Taylor
International Journal of Cardiology | ELSEVIER IRELAND LTD | Published : 2020
BACKGROUND: Paroxysmal atrial fibrillation (PAF) is associated with cardioembolic risk, however events may occur during sinus rhythm (SR). 4D-flow cardiac magnetic resonance (CMR) imaging allows visualisation of left atrial blood flow, to determine the residence time distribution (RTD), an assessment of atrial transit time. OBJECTIVE: To determine if atrial transit time is prolonged in PAF patients during SR, consistent with underlying atrial stasis. METHOD: 91 participants with PAF and 18 healthy volunteers underwent 4D flow analysis in SR. Velocity fields were produced RTDs, calculated by seeding virtual 'particles' at the right upper pulmonary vein and counting them exiting the mitral val..View full abstract
This was an investigator-initiated study. Funding for the study as provided by a grant from Monash Institute of Medical Engineering (MIME).