Journal article

Treatment of neurodegenerative diseases

undefined CHRISTOPHER HOVENS, undefined NIALL CORCORAN

Published : 2007

Abstract

The present invention relates to the use of selenate or a pharmaceutically acceptable salt thereof in methods and compositions for enhancing the activity of the protein phosphatase PP2A. Methods of reducing phosphorylation of tau protein, inhibiting activity of GSK3 and treating or preventing neurodegenerative diseases are also described.