Journal article

The association between maternal renal function and pregnancy outcomes in type 1 and type 2 diabetes

Jas-mine Seah, Ning Mao Kam, Lydia Wong, Cara Tanner, Richard J MacIsaac, Alexis Shub, Elif I Ekinci, Christine Houlihan

Diabetes Research and Clinical Practice | ELSEVIER IRELAND LTD | Published : 2020

Abstract

AIMS: To investigate the prognostic value of estimated glomerular filtration rate (eGFR) and albuminuria in determining pregnancy outcomes in women with type 1 and type 2 diabetes. METHODS: An observational study of pregnant women with type 1 (n = 92) and type 2 diabetes (n = 106) who delivered between 2004 and 2014 at a single tertiary obstetric centre. Clinical and biochemical characteristics were determined and related to major obstetric outcomes: preeclampsia, preterm birth <32 and <37 weeks, and neonatal intensive care admission. We used univariate analyses and multivariable logistic regression models with eGFR using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equati..

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