Dexmedetomidine infusion overdose during anesthesia: A case report
Christine Li, Michael Clifford
PEDIATRIC ANESTHESIA | WILEY | Published : 2020
A 12-kg infant was given intravenous dexmedetomidine 0.2 µg kg-1 min-1 as an adjunct for general anesthesia. The 60-fold increase in dexmedetomidine infusion rate caused a biphasic response with initial hypertension followed by bradycardia and hypotension requiring inotropic support. No postoperative or long-term sequelae were noted. Dexmedetomidine infusion is usually delivered as µg kg-1 h-1 .