Journal article

Mineralisation within human tooth cementum identified by secondary ion mass spectrometry

Marija Edinborough, Matthew Pilgrim, Sarah Fearn, Andrijana Cvetkovic, Branko Mihailovic, Rade Grbic, Kevan Edinborough

Journal of Analytical Atomic Spectrometry | ROYAL SOC CHEMISTRY | Published : 2020

Abstract

Life-history parameters such as pregnancies, skeletal trauma, and renal disease have previously been identified from hypomineralised growth layers (incremental lines) of acellular extrinsic fibre cementum (AEFC) using optical microscopy. We show that the precise periodicity of these growth layers remains poorly understood, so life history parameters for putative cementum deposition periodicity cannot be rigorously calculated. In an attempt to better understand the underlying formation processes, our study investigates whether or not mineralisation of AEFC incremental lines clearly indicate life history parameters in an ideal sample, using light microscopy, electron microscopy, and Time-of-Fl..

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Grants

Awarded by European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie actions, project EUROLIFE


Funding Acknowledgements

The authors thank Stepan Shennan and Eric Reynolds for providing useful comments on earlier versions of the paper. They also thank Bisa Radovi and Boidar Miloevi for enabling the research collaboration with the University of Pritina. Analysis of dental samples was carried out in the framework of the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie actions, project EUROLIFE (grant agreement No. 656203) awarded to M. E.