Journal article

The MSReactor computerized cognitive battery correlates with the processing speed test in relapsing-remitting multiple sclerosis

Charmaine Yam, Daniel Merlo, Jim Stankovich, David Darby, Melissa Gresle, Tomas Kalincik, Trevor J Kilpatrick, Jeanette Lechner-Scott, Bruce Taylor, Michael Barnett, Helmut Butzkueven, Anneke van der Walt

Multiple Sclerosis and Related Disorders | ELSEVIER SCI LTD | Published : 2020


BACKGROUND: Monitoring and screening of cognitive function in the ambulatory setting requires simple, brief cognitive tests that are reproducible. MSReactor (MSR) is a web-based platform that screens psychomotor (processing) speed, attention and working memory using a game-like interface. The Processing Speed Test (PST) is a validated computerized version of the Symbol Digit Modalities test (SDMT) and component of the Multiple Sclerosis Performance Test (MSPT). OBJECTIVE: To determine the baseline and 6-month predictive correlations between the MSReactor computerised cognitive battery and the PST. METHODS: Prospectively enrolled relapsing-remitting multiple sclerosis (RRMS) patients complete..

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Awarded by Novartis Australia

Funding Acknowledgements

MSReactor received unrestricted funding from Novartis Australia (grant number CFTY720D2418T) and Biogen (no grant number). PST data acquisition was supported by Biogen as part of the IMPROVE-MS (Australia protocol).