Coagulation in liver surgery: an observational haemostatic profile and thromboelastography study
June Oo, Megan Allen, Benjamin PT Loveday, Nora Lee, Brett Knowles, Bernhard Riedel, Kate Burbury, Benjamin Thomson
ANZ JOURNAL OF SURGERY | WILEY | Published : 2020
BACKGROUND: International normalized ratio (INR) is used as a marker of the haemostatic status following liver resection. However, the impact of liver resection on haemostasis is complex and beyond what can be measured by INR. This study aimed to prospectively assess haemostatic profile following liver resection and determine if INR measurement can safely guide post-operative thromboprophylaxis. METHODS: In this prospective cohort study, patients undergoing liver resection had coagulation parameters (International normalised ratio (INR), prothrombin time (PT), activated partial thromboplastin time, fibrinogen, d-dimer, von Willebrand factor antigen, procoagulant activity of phospholipids and..View full abstract
Haematological testing for this study was funded by Feilman Foundation, Perth, Western Australia.