Journal article

Adolescent and young adult mental health problems and infant offspring behavior: Findings from a prospective intergenerational cohort study

Primrose Letcher, Christopher J Greenwood, Helena Romaniuk, Elizabeth Spry, Jacqui A Macdonald, Helena McAnally, Kimberly C Thomson, George Youssef, Delyse Hutchinson, Jennifer McIntosh, Ann Sanson, Joanne Ryan, Ben Edwards, Judith Sligo, Robert J Hancox, George C Patton, Craig A Olsson

Journal of Affective Disorders | ELSEVIER | Published : 2020

Abstract

BACKGROUND: Parental depression and anxiety have been consistently linked to offspring behavior problems across childhood. However, many of the risks for these common mental health problems are established well before pregnancy. This study takes advantage of rare, prospective data to examine relations between parental mental health histories (from adolescence onwards) and next generation offspring behavior problems. METHODS: Data were drawn from a multi-generational cohort study that has followed Australians from infancy to adulthood since 1983, and 1171 of their offspring assessed prospectively from pregnancy. Generalized estimating equation models were used to estimate associations between..

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Grants

Awarded by Australian Research Council


Awarded by National Health and Medical Research Council of Australia


Awarded by National Health and Medical Research Council fellowship


Funding Acknowledgements

This work was supported by the Australian Research Council [DP130101459; DP160103160; DP180102447] and the National Health and Medical Research Council of Australia[APP1082406]. CAO is supported by a National Health and Medical Research Council fellowship [Investigator grant APP1175086].