Incremental prognostic value of echocardiography of left ventricular remodeling and diastolic function in STICH trial.
Kyung-Hee Kim, Lilin She, Kerry L Lee, Rafal Dabrowski, Paul A Grayburn, Miroslaw Rajda, David L Prior, Patrice Desvigne-Nickens, William A Zoghbi, Michele Senni, Guglielmo Stefanelli, Cesare Beghi, Thao Huynh, Eric J Velazquez, Jae K Oh, Grace Lin
Cardiovascular Ultrasound | Published : 2020
AIMS: We sought to determine which echocardiographic markers of left ventricular (LV) remodeling and diastolic dysfunction can contribute as incremental and independent prognostic information in addition to current clinical risk markers of ischemic LV systolic dysfunction in the Surgical Treatment for Ischemic Heart Failure (STICH) trial. METHODS AND RESULTS: The cohort consisted of 1511 of 2136 patients in STICH for whom baseline transmitral Doppler (E/A ratio) could be measured by an echocardiographic core laboratory blinded to treatment and outcomes, and prognostic value of echocardiographic variables was determined by a Cox regression model. E/A ratio was the most significant predictor o..View full abstract
Awarded by Foundation for the National Institutes of Health