Journal article

High prevalence of symptomatic spinal stenosis in Norwegian adults with achondroplasia: a population-based study

Svein O Fredwall, Unni Steen, Olga de Vries, Cecilie F Rustad, Heidi Beate Eggesbo, Harald Weedon-Fekjaer, Ingeborg B Udal, Ravi Savarirayan, Grethe Manum

Orphanet Journal of Rare Diseases | BMC | Published : 2020


BACKGROUND: Symptomatic spinal stenosis (SSS) is a well-known medical complication in achondroplasia. The reported prevalence of SSS is 10 to 30%, an estimate based on small studies or selected populations. No population-based studies exist currently. Furthermore, the relationship between SSS and physical functioning has not been investigated in detail. The aims of this study were to describe the prevalence of SSS in Norwegian adults with achondroplasia, and to explore the impact of SSS on physical functioning. METHODS: This was a population-based study on Norwegian community-dwelling adults with genetically confirmed achondroplasia. Prevalence of SSS was defined by clinical symptoms, and co..

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