Immunological responses and potency of the EG95NC(-) recombinant sheep vaccine against cystic echinococcosis
M Jazouli, MW Lightowlers, Z Bamouh, CG Gauci, K Tadlaoui, MM Ennaji, M Elharrak
PARASITOLOGY INTERNATIONAL | ELSEVIER IRELAND LTD | Published : 2020
Cystic echinococcosis (CE) is a zoonotic disease caused by the cestode parasite Echinococcus granulosus. The disease has an important impact on human health as well as economic costs including the cost of treatment as well as loss of productivity for the livestock industry. In many parts of the world where the disease is endemic, sheep and other livestock play an important role in the parasite's transmission. A vaccine to protect livestock against CE can be effective in reducing transmission and economic costs of the disease. A recombinant antigen vaccine has been developed against infection with E. granulosus (EG95) which could potentially be used to reduce the level of E. granulosus transm..View full abstract
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Awarded by National Health and Medical Research Council (NHMRC) of Australia
The study was sponsored by MCI Sante Animale, Morocco the staff of which were involved in the study design, collection, analysis and interpretation of data, writing the report and the decision to submit the article for publication. Funding is also acknowledged from the National Health and Medical Research Council (NHMRC) of Australia grant 1105448 (MWL), which played no role in in the study design, collection, analysis or interpretation of data, writing the report and the decision to submit the article for publication.