Journal article
Bullous pemphigoid in infants: characteristics, diagnosis and treatment
A Schwieger-Briel, C Moellmann, B Mattulat, F Schauer, D Kiritsi, E Schmidt, C Sitaru, H Ott, JS Kern
Orphanet Journal of Rare Diseases | BMC | Published : 2014
Abstract
BACKGROUND: Bullous pemphigoid (BP) in infants is a rare but increasingly reported autoimmune blistering skin disease. Autoantibody reactivity is usually poorly characterized. Current guidelines do not address specific aspects of the infantile form of BP. The objectives of this study are to define clinical and diagnostic characteristics of infantile BP and develop a treatment algorithm.METHODS: Detailed characterization of a current case series of five infants with BP from our departments. Comprehensive analysis of all reported cases (1-12 months) with respect to clinical and laboratory characteristics, treatment and outcome.RESULTS: In total 81 cases were identified (including our own). The..
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Funding Acknowledgements
We would like to thank the patients and their families for participating in this study. We would further like to thank A. Bedorf and K. Thoma for expert technical assistance. The article processing charge was funded by the German Research Foundation (DFG) and the Albert Ludwigs University Freiburg in the funding program Open Access Publishing.