Journal article

Treatment of early-stage mycosis fungoides: results from the PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) study

P Quaglino, HM Prince, R Cowan, M Vermeer, E Papadavid, M Bagot, O Servitjie, E Berti, E Guenova, R Stadler, C Querfeld, AM Busschots, E Hodak, A Patsatsi, J Sanches, M Maule, J Yoo, M Kevin, P Fava, S Ribero Show all

BRITISH JOURNAL OF DERMATOLOGY | WILEY | Published : 2021

Abstract

BACKGROUND: The PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) study is a prospective analysis of an international database. Here we examine front-line treatments and quality of life (QoL) in patients with newly diagnosed mycosis fungoides (MF). OBJECTIVES: To identify (i) differences in first-line approaches according to tumour-nodes-metastasis-blood (TNMB) staging; (ii) parameters related to a first-line systemic approach and (iii) response rates and QoL measures. METHODS: In total, 395 newly diagnosed patients with early-stage MF (stage IA-IIA) were recruited from 41 centres in 17 countries between 1 January 2015 and 31 December 2018 following central clinicopath..

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Grants

Awarded by Cancer Research UK


Awarded by European Academy of Dermatology and Venereology


Awarded by Krebsliga Schweiz


Awarded by Promedica Stiftung


Awarded by Fondo de Investigacion para la Salud


Awarded by NIH/NCI Cancer Center Support Grant


Awarded by NIH/NCI


Awarded by Leukemia Lymphoma Society Clinical Scholar Award


Funding Acknowledgements

This work was supported by Cancer Research UK (50763/A18021; to J.J.S.); the European Academy of Dermatology and Venereology (2014-23; to J.J.S.); the Spatz Foundation, Sundown Endowment Legacy (to Y.K.); Krebsliga Schweiz (KFS-4243-08-2017; to E. Guenova); Promedica Stiftung 1406/M and 1412/M (to E. Guenova); Fondo de Investigacion para la Salud (PI17/00957; to P.O.-R.); and an NIH/NCI Cancer Center Support Grant (P30CA033572) to the City of Hope, NIH/NCI grant (R01 CA229510-01) and Leukemia Lymphoma Society Clinical Scholar Award (CDP-14110-18; to C.Q.).