Emergent pattern formation in an interstitial biofilm
Cameron Zachreson, Christian Wolff, Cynthia B Whitchurch, Milos Toth
PHYSICAL REVIEW E | AMER PHYSICAL SOC | Published : 2017
Collective behavior of bacterial colonies plays critical roles in adaptability, survivability, biofilm expansion and infection. We employ an individual-based model of an interstitial biofilm to study emergent pattern formation based on the assumptions that rod-shaped bacteria furrow through a viscous environment and excrete extracellular polymeric substances which bias their rate of motion. Because the bacteria furrow through their environment, the substratum stiffness is a key control parameter behind the formation of distinct morphological patterns. By systematically varying this property (which we quantify with a stiffness coefficient γ), we show that subtle changes in the substratum stif..View full abstract
Awarded by Australian Research Council
C.Z. would like to acknowledge Matthew Arnold, Prabhakar Ranganathan, and Jared Cullen for useful discussions. This work was funded by FEI Company and the Australian Research Council (DP140102721 and CE110001018).