Leisure-Time Physical Activity Versus Sedentary Behaviour in Relation to Colorectal Adenoma and Cancer: Are these Two Distinct Risk Factors?
Shahid Mahmood, Robert J MacInnis, Amalia Karahalios, Dallas R English, Brigid M Lynch
CURRENT COLORECTAL CANCER REPORTS | SPRINGER | Published : 2020
Purpose of Review: This literature review provides an up-to-date overview of the evidence relating to the associations of leisure-time physical activity and sedentary behaviour with the risk of colorectal adenoma and cancer. A summary of possible biological mechanisms underpinning these associations is also presented. Recent Findings: Leisure-time physical activity and sedentary behaviour are often conceptualised as independent risk factors for colorectal adenoma and cancer. Regular leisure-time physical activity is associated with a 20%–25% reduction in colorectal cancer risk and an estimated 16% reduction in colonic adenoma. The risk estimates are similar for males and females, and for pro..View full abstract
Awarded by Victorian Cancer Agency
Brigid M. Lynch is supported by a Fellowship from the Victorian Cancer Agency (MCRF-18005).