Journal article

Comparison of cognitive dysfunction between schizophrenia and bipolar disorder patients: A meta -analysis of comparative studies

Wen Li, Fu-Chun Zhou, Ling Zhang, Chee H Ng, Gabor S Ungvari, Jun Li, Yu-Tao Xiang

Journal of Affective Disorders | ELSEVIER | Published : 2020

Abstract

OBJECTIVE: Cognitive dysfunction is common in both schizophrenia and bipolar disorder. This is a meta-analysis of studies that compared cognitive dysfunction between schizophrenia and bipolar disorder. METHODS: Both international and Chinese databases were systematically searched. Studies that compared cognitive function between schizophrenia and bipolar disorder with the MATRICS Consensus Cognitive Battery (MCCB) were analyzed using the random-effects model. RESULTS: Twelve studies with 9,518 participants (4,411 schizophrenia and 5,107 bipolar patients) were included in the analyses. Schizophrenia patients performed significantly worse than bipolar patients on the MCCB total scores with a l..

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University of Melbourne Researchers

Grants

Awarded by University of Macau


Awarded by National Key Research & Development Program of China


Awarded by Beijing Municipal Administration of Hospitals Incubating Program


Awarded by Beijing Municipal Administration of Hospitals' Ascent Plan


Funding Acknowledgements

The study was supported by the University of Macau (MYRG2016-00005-FHS; MYRG2019-00066-FHS), the National Key Research & Development Program of China(No. 2016YFC1307200), the Beijing Municipal Administration of Hospitals Incubating Program(No. PX2016028) and the Beijing Municipal Administration of Hospitals' Ascent Plan(No. DFL20151801).