Journal article

Novel allergen discovery through comprehensivede novotranscriptomic analyses of 5 shrimp species

Shaymaviswanathan Karnaneedi, Roger Huerlimann, Elecia B Johnston, Roni Nugraha, Thimo Ruethers, Aya C Taki, Sandip D Kamath, Nicholas M Wade, Dean R Jerry, Andreas L Lopata

Cold Spring Harbor Laboratory

Abstract

AbstractShellfish allergy affects up to 2% of the world’s population and persists for life in most patients. The diagnosis of a shellfish allergy, in particular shrimp, is however often challenging due to the similarity of allergenic proteins in other invertebrates. Despite the clinical importance, the complete allergen repertoire of allergy-causing shrimps remains unclear. Here we mine the complete transcriptome of five frequently consumed shrimp species to identify and compare allergens with all known allergen sources. The transcriptomes were assembledde novofrom raw RNA-Seq data of the whiteleg shrimp (Litopenaeus vannamei), black tiger shrimp (Penaeus monodon), banana shrimp (Fenneropena..

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University of Melbourne Researchers

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