Journal article

Cutaneous leiomyosarcoma: dermal and subcutaneous

Gwyneth Natalie Wong, Angela Webb, David Gyorki, Chris McCormack, Phillip Tran, Samuel Y Ngan, John Slavin, Michael A Henderson

AUSTRALASIAN JOURNAL OF DERMATOLOGY | WILEY | Published : 2020

Abstract

BACKGROUND AND OBJECTIVES: Leiomyosarcoma of skin (LMS) can be sub-classified on pathology appearances as Dermal or Subcutaneous. The aim of this study was to provide treatment recommendations for these uncommon tumours. METHODS: A retrospective review of all patients with dermal and subcutaneous leiomyosarcoma managed at the Peter MacCallum Cancer Centre, Australia from January 2003 to December 2018 was performed. Eighty-three patients were identified (64 dermal leiomyosarcoma, 19 subcutaneous leiomyosarcoma). RESULTS: Subcutaneous leiomyosarcoma were larger (median size 14 mm dermal, 49 mm subcutaneous, P = 0.01). No patient with a dermal leiomyosarcoma developed metastatic disease compare..

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