Increased risk of cervical dysplasia in females with autoimmune conditions-Results from an Australia database linkage study
Emma Foster, Michael J Malloy, Vilija G Jokubaitis, C David H Wrede, Helmut Butzkueven, Joe Sasadeusz, Sharon Van Doornum, Finlay Macrae, Gary Unglik, Julia ML Brotherton, Anneke van der Walt
PLoS One | PUBLIC LIBRARY SCIENCE | Published : 2020
BACKGROUND: Autoimmune conditions (AICs) and/or their treatment may alter risk of human papilloma virus (HPV) infection and females with AICs are therefore at an increased risk of cervical dysplasia. However, inclusion of these at-risk populations in cervical cancer screening and HPV-vaccination guidelines, are mostly lacking. This study aimed to determine the prevalence of cervical dysplasia in a wide range of AICs and compare that to HIV and immunocompetent controls to support the optimisation of cervical cancer preventive health measures. METHODS: Data linkage was used to match cervical screening episodes to emergency department records of females with AICs or HIV to immunocompetent contr..View full abstract
The data linkage for this study was funded by the Victorian Department of Health and Human Services. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.