Journal article

Increased risk of cervical dysplasia in females with autoimmune conditions-Results from an Australia database linkage study

Emma Foster, Michael J Malloy, Vilija G Jokubaitis, C David H Wrede, Helmut Butzkueven, Joe Sasadeusz, Sharon Van Doornum, Finlay Macrae, Gary Unglik, Julia ML Brotherton, Anneke van der Walt

PLoS One | PUBLIC LIBRARY SCIENCE | Published : 2020


BACKGROUND: Autoimmune conditions (AICs) and/or their treatment may alter risk of human papilloma virus (HPV) infection and females with AICs are therefore at an increased risk of cervical dysplasia. However, inclusion of these at-risk populations in cervical cancer screening and HPV-vaccination guidelines, are mostly lacking. This study aimed to determine the prevalence of cervical dysplasia in a wide range of AICs and compare that to HIV and immunocompetent controls to support the optimisation of cervical cancer preventive health measures. METHODS: Data linkage was used to match cervical screening episodes to emergency department records of females with AICs or HIV to immunocompetent contr..

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