Journal article

Increased risk of cervical dysplasia in females with autoimmune conditions-Results from an Australia database linkage study

E Foster, MJ Malloy, VG Jokubaitis, C David, H Butzkueven, J Sasadeusz, S van Doornum, F Macrae, G Unglik, JML Brotherton, A van der Walt

Plos One | PUBLIC LIBRARY SCIENCE | Published : 2020

Abstract

Background Autoimmune conditions (AICs) and/or their treatment may alter risk of human papilloma virus (HPV) infection and females with AICs are therefore at an increased risk of cervical dysplasia. However, inclusion of these at-risk populations in cervical cancer screening and HPV-vaccination guidelines, are mostly lacking. This study aimed to determine the prevalence of cervical dysplasia in a wide range of AICs and compare that to HIV and immunocompetent controls to support the optimisation of cervical cancer preventive health measures. Methods Data linkage was used to match cervical screening episodes to emergency department records of females with AICs or HIV to immunocompetent control..

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