Acoustic Speech Analytics Are Predictive of Cerebellar Dysfunction in Multiple Sclerosis
Gustavo Noffs, Frederique MC Boonstra, Thushara Perera, Scott C Kolbe, Jim Stankovich, Helmut Butzkueven, Andrew Evans, Adam P Vogel, Anneke van der Walt
CEREBELLUM | SPRINGER | Published : 2020
Speech production relies on motor control and cognitive processing and is linked to cerebellar function. In diseases where the cerebellum is impaired, such as multiple sclerosis (MS), speech abnormalities are common and can be detected by instrumental assessments. However, the potential of speech assessments to be used to monitor cerebellar impairment in MS remains unexplored. The aim of this study is to build an objectively measured speech score that reflects cerebellar function, pathology and quality of life in MS. Eighty-five people with MS and 21 controls participated in the study. Speech was independently assessed through objective acoustic analysis and blind expert listener ratings. Ce..View full abstract
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Awarded by NHMRC fellowship
This study was funded by NHMRC fellowship grants number 1085461 and 1082910.