Journal article

Predictors of overall survival following extended radical resections for locally advanced and recurrent pelvic malignancies

Joseph C Kong, Oliver Peacock, Peadar S Waters, Tim Eglinton, Satish K Warrier, Christopher Wakeman, Frank A Frizelle, Alexander G Heriot, Jacob J McCormick

Langenbeck's Archives of Surgery | SPRINGER | Published : 2020

Abstract

PURPOSE: In an era of personalised medicine, there is an overwhelming effort for predicting patients who will benefit from extended radical resections for locally advanced pelvic malignancy. However, there is paucity of data on the effect of comorbidities and postoperative complications on long-term overall survival (OS). The aim of this study was to define predictors of 1-year and 5-year OS. METHODS: Data were collected from prospective databases at two high-volume institutions specialising in beyond TME surgery for locally advanced and recurrent pelvic malignancies between 1990 and 2015. The primary outcome measures were 1-year and 5-year OS. RESULTS: A total of 646 consecutive extended ra..

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