Journal article
Comparative efficacy and acceptability of antidepressants, psychotherapies, and their combination for acute treatment of children and adolescents with depressive disorder: a systematic review and network meta-analysis
X Zhou, T Teng, Y Zhang, C Del Giovane, TA Furukawa, JR Weisz, X Li, P Cuijpers, D Coghill, Y Xiang, SE Hetrick, S Leucht, M Qin, J Barth, AV Ravindran, L Yang, J Curry, L Fan, SG Silva, A Cipriani Show all
Lancet Psychiatry | ELSEVIER SCI LTD | Published : 2020
Abstract
Background: Depressive disorders are common in children and adolescents. Antidepressants, psychotherapies, and their combination are often used in routine clinical practice; however, available evidence on the comparative efficacy and safety of these interventions is inconclusive. Therefore, we sought to compare and rank all available treatment interventions for the acute treatment of depressive disorders in children and adolescents. Methods: We did a systematic review and network meta-analysis. We searched PubMed, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, PsycINFO, ProQuest, CINAHL, LiLACS, international trial registries, and the websites of regulatory agenc..
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Awarded by University of Texas Southwestern Medical Center
Funding Acknowledgements
National Key Research and Development Program of China.