Understanding implementation success: protocol for an in-depth, mixed-methods process evaluation of a cluster randomised controlled trial testing methods to improve detection of Lynch syndrome in Australian hospitals
April Morrow, Katherine M Tucker, Tim J Shaw, Bonny Parkinson, Charles Abraham, Luke Wolfenden, Natalie Taylor
BMJ Open | BMJ PUBLISHING GROUP | Published : 2020
INTRODUCTION: In multisite intervention trials, implementation success often varies widely across settings. Process evaluations are crucial to interpreting trial outcomes and understanding contextual factors and causal chains necessary for successful implementation. Lynch syndrome is a hereditary cancer predisposition conferring an increased risk of colorectal, endometrial and other cancer types. Despite systematic screening protocols to identify Lynch syndrome, the condition remains largely underdiagnosed. The Hide and Seek Project ('HaSP') is a cluster randomised controlled trial determining the effectiveness of two approaches to improving Lynch syndrome detection at eight Australian hospi..View full abstract
AM is a recipient of an Australian Government Research Training Programme Scholarship and a Translational Cancer Research Network Clinical PhD Scholarship Top-up award, supported by the Cancer Institute NSW. Funding support has also been provided by Cancer Council NSW.