Diffraction-based acoustic manipulation in microchannels enables continuous particle and bacteria focusing.
Citsabehsan Devendran, Kyungyong Choi, Jongyoon Han, Ye Ai, Adrian Neild, David J Collins
Lab on a Chip | Royal Society of Chemistry | Published : 2020
Acoustic fields have shown wide utility for micromanipulation, though their implementation in microfluidic devices often requires accurate alignment or highly precise channel dimensions, including in typical standing surface acoustic wave (SSAW) devices and resonant channels. In this work we investigate an approach that permits continuous microscale focusing based on diffractive acoustics, a phenomenon where a time-averaged spatially varying acoustic pressure landscape is produced by bounding a surface acoustic wave (SAW) transducer with a microchannel. By virtue of diffractive effects, this acoustic field is formed with the application of only a single travelling wave. As the field is dicta..View full abstract
Awarded by Singapore Ministry of Education Academic Research Fund Tier 2
We would like to thank the Hung lab at Broad Institute for the provision of the fluorescent E. coli from which the samples used in this work were cultured. This work was supported by Singapore Ministry of Education Academic Research Fund Tier 2 (T2MOE1603) awarded to YA.