Journal article

Clinical components and associated behavioural aspects of a complex healthcare intervention: Multi-methods study of selective decontamination of the digestive tract in critical care

Stephan U Dombrowski, Maria E Prior, Eilidh Duncan, Brian H Cuthbertson, Geoff Bellingan, Marion K Campbell, Louise Rose, Alexander R Binning, Anthony C Gordon, Peter Wilson, Rob Shulman, Jill J Francis



BACKGROUND: This study sought to identify and describe the clinical and behavioural components (e.g. the what, how, when, where and by whom) of 'selective decontamination of the digestive tract' (SDD) as routinely implemented in the care of critically ill patients. METHODS: Multi-methods study, consisting of semi-structured observations of SDD delivery, interviews with clinicians and documentary analysis, conducted in two ICUs in the UK that routinely deliver SDD. Data were analysed within-site to describe clinical and behavioural SDD components and synthesised across-sites to describe SDD in context. RESULTS: SDD delivery involved multiple behaviours extending beyond administration of its c..

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University of Melbourne Researchers


Awarded by National Institute for Health Research

Awarded by Chief Scientist Office

Funding Acknowledgements

We would like to thank all the clinical staff who provided their time and expertise by participating in this study. This project was funded by the UK National Institute for Health Research (NIHR), Health Technology Assessment (HTA) programme. Visit the HTA programme website for more details ACG is a NIHR Clinician Scientists award holder, and is grateful for funding from the NIHR comprehensive Biomedical Research Centre funding stream. The Aberdeen Health Services Research Unit is funded by the Chief Scientist Office of the Scottish Government Health Directorates. The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the Department of Health or the Scottish Government Health Directorates.