Journal article
Theoretical and empirical dimensions of the Aberdeen Glaucoma Questionnaire: A cross sectional survey and principal component analysis
M Prior, CR Ramsay, JM Burr, SE Campbell, DJ Jenkinson, R Asoaka, JJ Francis
BMC Ophthalmology | BMC | Published : 2013
Abstract
Background: To develop patient-reported outcome instruments, statistical techniques (e.g., principal components analysis; PCA) are used to examine correlations among items and identify interrelated item subsets (empirical factors). However, interpretation and labelling of empirical factors is a subjective process, lacking precision or conceptual basis. We report a novel and reproducible method for mapping between theoretical and empirical factor structures. We illustrate the method using the pilot Aberdeen Glaucoma Questionnaire (AGQ), a new measure of glaucoma-related disability developed using the International Classification of Functioning and Disability (ICF) as a theoretical framework a..
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Awarded by Scottish Government Health and Social Care Directorate
Funding Acknowledgements
This study is one component of a Medical Research Council funded strategic grant, G0701759: Developing the intervention and outcome components of a proposed randomised controlled trial of a national screening programme for open angle glaucoma. The Health Services Research Unit receives a core grant from the Chief Scientists Office of the Scottish Government Health Directorates. The views expressed are those of the authors and not necessarily those of funding bodies. We thank Marion Campbell, Augusto Azuara-Blanco and Jemaima CheHamzah from the Glaucoma screening Platform Study research group for their contribution to the development of the larger study and their guidance throughout its conduct. We thank the Glaucoma screening Platform Study advisory panel including R Bativala, D Crabb, D Garway-Heath, R Hitchings, S McPherson, A Tuulonen, A Visvanathan and R Wormald for their guidance and contribution to development and oversight of the study and its findings.