Journal article

Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins

Julie Brittenden, David Cooper, Maria Dimitrova, Graham Scotland, Seonaidh C Cotton, Andrew Elders, Graeme MacLennan, Craig R Ramsay, John Norrie, Jennifer M Burr, Bruce Campbell, Paul Bachoo, Ian Chetter, Michael Gough, Jonothan Earnshaw, Tim Lees, Julian Scott, Sara A Baker, Emma Tassie, Jill Francis Show all

NEW ENGLAND JOURNAL OF MEDICINE | MASSACHUSETTS MEDICAL SOC | Published : 2019

Abstract

BACKGROUND: Endovenous laser ablation and ultrasound-guided foam sclerotherapy are recommended alternatives to surgery for the treatment of primary varicose veins, but their long-term comparative effectiveness remains uncertain. METHODS: In a randomized, controlled trial involving 798 participants with primary varicose veins at 11 centers in the United Kingdom, we compared the outcomes of laser ablation, foam sclerotherapy, and surgery. Primary outcomes at 5 years were disease-specific quality of life and generic quality of life, as well as cost-effectiveness based on models of expected costs and quality-adjusted life-years (QALYs) gained that used data on participants' treatment costs and s..

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University of Melbourne Researchers