Journal article

The effectiveness and cost-effectiveness of minimal access surgery amongst people with gastro-oesophageal reflux disease - a UK collaborative study. The REFLUX trial.

A Grant, S Wileman, C Ramsay, L Bojke, D Epstein, M Sculpher, S Macran, M Kilonzo, L Vale, J Francis, A Mowat, Z Krukowski, R Heading, M Thursz, I Russell, M Campbell, undefined REFLUX Trial Group

Health Technology Assessment | Published : 2008


OBJECTIVES: To evaluate the clinical effectiveness, cost-effectiveness and safety of a policy of relatively early laparoscopic surgery compared with continued medical management amongst people with gastro-oesophageal reflux disease (GORD) judged suitable for both policies. DESIGN: Relative clinical effectiveness was assessed by a randomised trial (with parallel non-randomised preference groups) comparing a laparoscopic surgery-based policy with a continued medical management policy. The economic evaluation compared the cost-effectiveness of the two management policies in order to identify the most efficient provision of future care and describe the resource impact that various policies for f..

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University of Melbourne Researchers