Journal article

Improving appropriate polypharmacy for older people in primary care: selecting components of an evidence-based intervention to target prescribing and dispensing

Cathal A Cadogan, Cristin Ryan, Jill J Francis, Gerard J Gormley, Peter Passmore, Ngaire Kerse, Carmel M Hughes



BACKGROUND: The use of multiple medicines (polypharmacy) is increasingly common in older people. Ensuring that patients receive the most appropriate combinations of medications (appropriate polypharmacy) is a significant challenge. The quality of evidence to support the effectiveness of interventions to improve appropriate polypharmacy is low. Systematic identification of mediators of behaviour change, using the Theoretical Domains Framework (TDF), provides a theoretically robust evidence base to inform intervention design. This study aimed to (1) identify key theoretical domains that were perceived to influence the prescribing and dispensing of appropriate polypharmacy to older patients by ..

View full abstract

University of Melbourne Researchers


Awarded by Dunhill Medical Trust

Funding Acknowledgements

This work was supported by The Dunhill Medical Trust [grant number: R298/0513]. The authors would like to thank all of the healthcare professionals who agreed to take part in the study. The authors would also like to thank Ms. Johanne Barry (Queen's University Belfast), Dr. Nigel Hart (Queen's University Belfast) and Dr. June Tordoff (University of Otago, New Zealand) for their feedback on the interview topic guides. The authors are especially grateful to Mrs. Claire Leathem and colleagues in the Northern Ireland Clinical Research Network for their assistance with participant recruitment.