Journal article

Functional segregation within the pelvic nerve of male rats: a meso- and microscopic analysis

Martin M Bertrand, Nadja Korajkic, Peregrine B Osborne, Janet R Keast

Journal of Anatomy | WILEY | Published : 2020

Abstract

The pelvic splanchnic nerves are essential for pelvic organ function and have been proposed as targets for neuromodulation. We have focused on the rodent homologue of these nerves, the pelvic nerves. Our goal was to define within the pelvic nerve the projections of organ-specific sensory axons labelled by microinjection of neural tracer (cholera toxin, subunit B) into the bladder, urethra or rectum. We also examined the location of peptidergic sensory axons within the pelvic nerves to determine whether they aggregated separately from sacral preganglionic and paravertebral sympathetic postganglionic axons travelling in the same nerve. To address these aims, microscopy was performed on the maj..

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Grants

Awarded by People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013)


Awarded by Stimulating Peripheral Activity to Relieve Conditions (SPARC) Program


Funding Acknowledgements

The Societe Interdisciplinaire Francophone d'UroDynamique et de Pelviperineologie (SIFUD-PP), Grant/Award Number: N/A; Faculty of Medicine of Montpellier-Nimes, Grant/Award Number: N/A; People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013), Grant/Award Number: PRESTIGE program, PCOFUND-GA-2013-609102; The Association Francaise de Chirurgie (AFC), Grant/Award Number: N/A; The University Hospital of Nimes, Grant/Award Number: N/A; Stimulating Peripheral Activity to Relieve Conditions (SPARC) Program, Grant/Award Number: OT2OD023872