Does Nasal Obstruction Induce Obstructive Sleep Apnea in Healthy Women?
Islay Pittaway, Anna Ishkova, Helena Bean, Stephanie McCarthy, Isabella Lay, Joanne Avraam, Andrew Dawson, Therese Thornton, Christian L Nicholas, John Trinder, Fergal J O'Donoghue, Melinda L Jackson, Amy S Jordan
NATURE AND SCIENCE OF SLEEP | DOVE MEDICAL PRESS LTD | Published : 2020
Purpose: Obstructive sleep apnea (OSA) is less prevalent among women and is associated with different symptoms and consequences to OSA in men. The reasons for these differences are unknown and difficult to tease apart in clinical populations. If OSA could be temporarily induced in healthy men and women, the causes of some of these differences could be investigated. Nasal blocking has been used to induce OSA in healthy men but its effect in women has not been reported. Patients and Methods: A total of 14 healthy individuals (10 women) underwent in-laboratory diagnostic sleep studies on two occasions separated by a week. On one occasion, the nasal passages were blocked, whereas on the other oc..View full abstract
Awarded by Australian Research Council
A/Prof Jordan and the study were supported by an Australian Research Council Future Fellowship (FT100100203). The sponsor did not have any role in any stage from the design of the study to submission.