Journal article

Prevalence of MRI abnormalities in people with epilepsy in rural China

I Davagnanam, Z Chen, C Hoskote, D Ding, B Yang, Y Wang, T Wang, W Li, JS Duncan, W Wang, JW Sander, P Kwan

Neurology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020

Abstract

ObjectiveTo assess the prevalence of brain MRI abnormalities in people with epilepsy in rural China and to compare it with that of individuals in the United Kingdom.MethodsBrain MRI scans were obtained in people with epilepsy who participated in a rural community-based program in China between July 2010 and December 2012. Individual epileptogenic lesion types were reviewed and their associations with seizure control examined. The MRI findings were compared with 2 previous similar studies in the United Kingdom.ResultsAmong the 597 individuals (58% male, median age 38 years) with MRI scans analyzed, 488 (82%) had active epilepsy. The MRI was abnormal in 389 individuals (65%), with potentially ..

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University of Melbourne Researchers

Grants

Awarded by National Institutes of Health


Funding Acknowledgements

This study was supported by a National Institute of Neurological Disorders and Stroke/Fogarty grant (R21NS069223-01) and Key Research Project of the Chinese Ministry of Science and Technology (2016YFC0904400).