Journal article

Prevalence of MRI abnormalities in people with epilepsy in rural China

Indran Davagnanam, Zhibin Chen, Chandrashekar Hoskote, Ding Ding, Bin Yang, Yingli Wang, Taiping Wang, Wenling Li, John S Duncan, Wenzhi Wang, Josemir W Sander, Patrick Kwan

Neurology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020

Abstract

OBJECTIVE: To assess the prevalence of brain MRI abnormalities in people with epilepsy in rural China and to compare it with that of individuals in the United Kingdom. METHODS: Brain MRI scans were obtained in people with epilepsy who participated in a rural community-based program in China between July 2010 and December 2012. Individual epileptogenic lesion types were reviewed and their associations with seizure control examined. The MRI findings were compared with 2 previous similar studies in the United Kingdom. RESULTS: Among the 597 individuals (58% male, median age 38 years) with MRI scans analyzed, 488 (82%) had active epilepsy. The MRI was abnormal in 389 individuals (65%), with pote..

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Grants

Awarded by National Institute of Neurological Disorders and Stroke/Fogarty grant


Awarded by Key Research Project of the Chinese Ministry of Science and Technology


Funding Acknowledgements

This study was supported by a National Institute of Neurological Disorders and Stroke/Fogarty grant (R21NS069223-01) and Key Research Project of the Chinese Ministry of Science and Technology (2016YFC0904400).