Journal article
Thrombolysis outcomes in acute ischemic stroke by fluid-attenuated inversion recovery hyperintense arteries
Z Zhou, S Yoshimura, C Delcourt, RI Lindley, S You, A Malavera, T Torii-Yoshimura, C Carcel, X Wang, X Chen, MW Parsons, AM Demchuk, JM Wardlaw, G Mair, TG Robinson, J Chalmers, J Xu, CS Anderson
Stroke | Published : 2020
Abstract
BACKGROUND AND PURPOSE: To determine factors associated with fluid-attenuated inversion recovery (FLAIR) hyperintense arteries (FLAIR-HAs) on magnetic resonance imaging and their prognostic significance in thrombolysis-treated patients with acute ischemic stroke from the ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) trial alteplase-dose arm. METHODS: Patients with acute ischemic stroke (N=293) with brain magnetic resonance imaging (FLAIR and diffusion-weighted imaging sequences) scanned <4.5 hours of symptom onset were assessed for location and extent (score) of FLAIR-HAs, infarct volume, large vessel occlusion (LVO), and other ischemic signs. Logistic regression..
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Funding Acknowledgements
The funding information of the ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) trial is listed in Reference 2.