Journal article

Developmental outcomes following vaccine-proximate febrile seizures in children

Lucy Deng, Nicholas Wood, Kristine Macartney, Michael Gold, Nigel Crawford, Jim Buttery, Peter Richmond, Belinda Barton



OBJECTIVE: To compare the developmental and behavioral outcomes of children experiencing an initial vaccine-proximate (VP) febrile seizure (FS) to those having a non-VP-FS (NVP-FS) and controls who have not had a seizure. METHODS: In this prospective multicenter cohort study, children with their first FS before 30 months of age between May 2013 and April 2016 were recruited from 4 Australian pediatric hospitals and classified as having VP-FS or NVP-FS. Similar-aged children with no seizure history were recruited as controls. The Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) was administered to participants with FS 12 to 24 months after their initial FS and to co..

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Awarded by Australian National Health and Medical Research Council (NHMRC)

Awarded by NHMRC Career Development Fellowship

Funding Acknowledgements

This study was funded by Australian National Health and Medical Research Council (NHMRC) Project Grant 1049557. Dr. Deng is supported by the University of Sydney Research Training Program scholarship. Dr. Nicholas Wood is supported by an NHMRC Career Development Fellowship (APP1063629).