Journal article

High-performance thin -layer chromatography fingerprinting, total phenolic and total flavonoid contents and anti -platelet -aggregation activities of Prosopis farcta extracts

Farzad Kobarfard, Seyed Abdulmajid Ayatollahi, Nafiseh Khosravi-Dehaghi, Mehrdad Faizi, Salimeh Amidi, Miquel Martorell, Muhammad Iqbal Choudhary, Hafiz Ansar Rasul Suleria, Javad Sharifi-Rad

CELLULAR AND MOLECULAR BIOLOGY | C M B ASSOC | Published : 2020

Abstract

Cardiovascular diseases are a leading cause of worldwide death and excessive platelet is closely related with their pathogenesis. Different plants and natural compounds have demonstrated anti-platelet effects. The aim of this study was to report the high-performance thin-layer chromatography (HPTLC) fingerprinting and anti-platelet-aggregation activities of different leaf extracts (n-hexane, chloroform, ethyl acetate, methanol and aqueous) of Prosopis farcta (Syrian mesquite) plant. The results showed a 100% inhibition of aggregation activity after plasmatic adenosine diphosphate (ADP) aggregation activation of ethyl acetate, ethanolic, methanolic and aqueous extracts, at 60 mg/mL concentrat..

View full abstract

University of Melbourne Researchers