Are Leading Risk Factors for Cancer and Mental Disorders Multimorbidity Shared by These Two Individual Conditions in Community-Dwelling Middle-Aged Adults?
Xianwen Shang, Allison M Hodge, Wei Peng, Mingguang He, Lei Zhang
Cancers | MDPI | Published : 2020
Data on the leading shared risk factors of cancer and mental disorders are limited. We included 98,958 participants (54.8% women) aged 45-64 years from the 45 and Up Study who were free of cancer, depression, and anxiety at baseline (2006-2009). The incidence of cancer, mental disorders, and multimorbidity (concurrent cancer and mental disorders) was identified using claim databases during follow-up until 31 December 2016. During a nine-year follow-up, the cumulative incidence of cancer, mental disorders, and multimorbidity was 8.8%, 17.4%, and 2.2%, respectively. Participants with cancer were 3.41 times more likely to develop mental disorders, while individuals with mental disorders were 3...View full abstract
Awarded by Fundamental Research Funds of the State Key Laboratory in Ophthalmology, National Natural Science Foundation of China
Awarded by National Natural Science Foundation of China
Awarded by Outstanding Young Scholars Funding
Awarded by Xi'an Jiaotong University Basic Research and Profession Grant
Awarded by Epidemiology modeling and risk assessment
Awarded by Xi'an Jiaotong University Young Talent Support Grant
This specific project was funded by the Australia China Research Accelerator Program at Centre for Eye Research Australia. Professor Mingguang He is also supported by the Fundamental Research Funds of the State Key Laboratory in Ophthalmology, National Natural Science Foundation of China (81420108008). The funders were not involved in the research and preparation of the article, including study design; collection, analysis, and interpretation of data; writing of the article; or in the decision to submit it for publication. Professor Lei Zhang is also supported by the National Natural Science Foundation of China (Grant number: 81950410639); Outstanding Young Scholars Funding (Grant number: 3111500001), Xi'an Jiaotong University Basic Research and Profession Grant (Grant number: xtr022019003, xzy032020032), Epidemiology modeling and risk assessment (Grant number: 20200344), and Xi'an Jiaotong University Young Talent Support Grant (Grant number: YX6J004).