Journal article

The Melanoma Genomics Managing Your Risk Study randomised controlled trial: statistical analysis plan.

Serigne N Lo, Amelia K Smit, David Espinoza, Anne E Cust, undefined Managing Your Risk Study Group

Trials | Published : 2020

Abstract

BACKGROUND: The Melanoma Genomics Managing Your Risk Study is a randomised controlled trial that aims to evaluate the efficacy of providing information on personal genomic risk of melanoma in reducing ultraviolet radiation (UV) exposure, stratified by traditional risk group (low or high phenotypic risk) in the general population. The primary outcome is objectively measured total daily Standard Erythemal Doses at 12 months. Secondary outcomes include UV exposure at specific time periods, self-reported sun protection and skin-examination behaviours, psychosocial outcomes, and ethical considerations surrounding offering genomic testing at a population level. A within-trial and modelled economic..

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