Computational study on synovial fluid flow behaviour in cartilage contact gap under osteoarthritic condition
JinJing Liao, Saeed Miramini, Xuanchi Liu, Lihai Zhang
Computers in Biology and Medicine | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2020
This study numerically investigates the pathological changes of fluid flow in cartilage contact gap due to the changes in cartilage surface roughness and synovial fluid characteristics in osteoarthritic (OA) condition. First, cartilage surface topographies in both healthy and OA conditions are constructed using a numerical approach with consideration of both vertical and horizontal roughness. Then, constitutive equations for synovial fluid viscosity are obtained through calibration against previous experimental data. Finally, the roughness and synovial fluid information are input into the gap flow model to predict the gap permeability. The results show that the rougher surface of OA cartilag..View full abstract
The authors would like to acknowledge the funding support by a Graduate Research Scholarship of The University of Melbourne.