Journal article

Computational study on synovial fluid flow behaviour in cartilage contact gap under osteoarthritic condition

JinJing Liao, Saeed Miramini, Xuanchi Liu, Lihai Zhang

Computers in Biology and Medicine | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2020

Abstract

This study numerically investigates the pathological changes of fluid flow in cartilage contact gap due to the changes in cartilage surface roughness and synovial fluid characteristics in osteoarthritic (OA) condition. First, cartilage surface topographies in both healthy and OA conditions are constructed using a numerical approach with consideration of both vertical and horizontal roughness. Then, constitutive equations for synovial fluid viscosity are obtained through calibration against previous experimental data. Finally, the roughness and synovial fluid information are input into the gap flow model to predict the gap permeability. The results show that the rougher surface of OA cartilag..

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