Journal article

Cardiorespiratory and autonomic function in epileptic seizures: A video-EEG monitoring study

Shobi Sivathamboo, Thomas N Constantino, Zhibin Chen, Paul B Sparks, Jeremy Goldin, Dennis Velakoulis, Nigel C Jones, Patrick Kwan, Vaughan G Macefield, Terence J O'Brien, Piero Perucca

EPILEPSY & BEHAVIOR | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2020

Abstract

PURPOSE: Seizure-induced cardiorespiratory and autonomic dysfunction has long been recognized, and growing evidence points to its implication in sudden unexpected death in epilepsy (SUDEP). However, a comprehensive understanding of cardiorespiratory function in the preictal, ictal, and postictal periods are lacking. METHODS: We examined continuous cardiorespiratory and autonomic function in 157 seizures (18 convulsive and 139 nonconvulsive) from 70 consecutive patients who had a seizure captured on concurrent video-encephalogram (EEG) monitoring and polysomnography between February 1, 2012 and May 31, 2017. Heart and respiratory rates, heart rate variability (HRV), and oxygen saturation were..

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